Rationale
We begin our research endeavors with a solid foundation for study design
and methodology. We have conducted systematic reviews of the current
state of computerized assessments, led focus groups with primary care
physicians to learn about their confidence and methods for diagnosing
brain disorders, and reviewed qualitative results from feasibility
studies in primary care settings.
Validation
We believe all novel assessments should be backed with evidence-based
support before being used in clinical care. We have performed several
types of validation with our tasks with sensitivity and specificity
analyses, concurrent validity analyses, neuroanatomical validity
analyses, and validation in several language adaptations across the
globe.
Biomarkers
Studies aimed at discovering links between TabCAT and biomarkers play a
crucial role in early detection and diagnosis, treatment monitoring over
time, and predicting change over time. We have seen significant
associations between our tests and Aβ-PET and tau-PET status, and
continue to perform research in this exciting field.
Underserved Populations
We believe in health equity for all, and the need for accessible tools
is growing. We continue to validate our tools in multiple language
adaptations, examine social determinants of health, and explore
neurocognitive disorders in underserved populations such as those
experiencing homelessness.